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10.1016/j.toxlet.2018.01.020 63 HuangS.FrangogiannisN

1 Next Steps and Future Implications These early insights from the COURAGE trial are consistent with recently published pre-clinical data in rodents and non-human primates and clearly establish the principle that blocking GDF8 with or without activin A can preserve muscle and further increase fat loss in patients being treated with GLP-1 therapy, thereby improving the quality of weight loss, continued Yancopoulos, in the press release

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